Release date: 2007-12-10

Research indicates that CBP technology can alleviate oxidative damage in patients with MODS. Liu Hongbao, MD, of the Department of Radiology, Xijing Hospital, Fourth Military Medical University, etc., based on his research and related clinical research on the evaluation and mechanism of continuous blood purification in critical illness treatment In practice, it was concluded that continuous blood purification (CBP) technology can alleviate oxidative damage in patients with multiple organ dysfunction syndrome (MODS). According to reports, CBP is no longer limited to replacing kidney function. It also exerts the effect unmatched by traditional medical treatment methods in the treatment of critical illnesses such as severe infection, trauma, poisoning and MODS. How to grasp the timing, treatment and treatment dose of CBP according to different conditions of patients, and to explore its therapeutic mechanism is always a hot spot in clinical research. In this regard, under the guidance of Professor Chen Wei, Director of the Department, Liu Hongbao et al. conducted in-depth research on the efficacy and mechanism of CBP clinical application.
In the study, they first proposed that CBP technology can improve the oxidative stress status and reduce oxidative damage in patients with MODS. The concept of early prevention of CBP in patients with MODS is proposed. The key to improving the survival rate of MODS patients is early diagnosis and timely. CBP treatment. The researchers also applied low-sugar formula replacement fluid and plasma dialysis combined with high-volume hemofiltration (HVHF) technology to the clinic earlier in China, and earlier confirmed the dynamic APACHE score, MODS score and cells during CBP treatment. The detection of factors can comprehensively judge the prognosis of patients and guide the adjustment of CBP program, and confirm that increasing the replacement rate is more conducive to clearing inflammatory mediators and improving immune status. It is reported that so far, researchers have applied CBP technology to effectively treat 411 cases of various critical illnesses. The methods have been promoted in 9 hospitals such as Xi'an Central Hospital, Sanmenxia Yellow River Hospital of Henan Province, and 323 Hospital of People's Liberation Army. Good social and economic benefits. Not long ago, the research results won the second prize of military medical results. ——Midi Medical Network

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