Among the many pharmaceutical dosage forms, the granules have received extensive attention because of their advantages such as rapid onset of treatment, simple preparation process, and convenient taking. However, in production, how to control the packaging quality of granules and obtain satisfactory filling accuracy has always plagued many pharmaceutical companies. MediSeal GmbH is a manufacturer specializing in the production of pharmaceutical packaging equipment. It has a history of producing blister packaging and carton production lines, four-side sealing pouch packaging and cartoning production lines for 70 years. The equipment is designed and manufactured to meet the production of pharmaceuticals. Current GMP regulatory requirements. Among them, the company's leading small bag packaging technology has been praised by the industry. Here, according to some performance and characteristics of the small bag packaging machine of the Madison, the introduction of the small bag packaging machine and its connection technology.

The pouch packaging machine for packaging granules and medicines generally has the structure of vertical design, intermittent operation and balcony type workstation. The machine can complete bag making, drug metering and bagging, pouch sealing, easy tearing, production batch embossing, pouch cutting, double-connected pouch connection dotted line in multi-channel operation (up to 10 channels) And other processes.

Bags ensure a good appearance

In order to make the pouch have a good appearance when making the bag, the Medic's pouch packaging machine adopts a whole-volume packaging film on-board method to realize online automatic rectification and centering cutting through the detection and control of the edge position of the packaging film roll. Align the edges of the bag with no waste edges. Thanks to the special shape of the medium-cutting cutter, no dust is generated even when the fibrous composite material is cut, and the inside of the bag is cleaned.

Cutting and metering design guarantees good filling accuracy

In the cutting and metering of medicines, the cutting system and metering system of Medicis is a modular design structure, each channel is independent and easy to disassemble and clean.

Cutting

In the process of blanking, metering and bagging of pharmaceutical materials, there are three sets of auxiliary devices for increasing the fluidity of the materials, namely: hopper agitator, metering chamber agitator, and electromagnetic oscillating device of the filling tube. The stirring speed, the action period and the electromagnetic oscillation strength can be set and controlled according to the fluidity of the material.

In order to avoid the dust pollution to the machine and remove the floating dust in the product to ensure the reliability of the small bag sealing, the company has equipped the static elimination device and the dust removal device in the equipment blanking system.

Metering

The metering method of the medicine is volumetric measurement. The unique adjustable piston measuring cup structure is used to adjust the measuring volume by changing the stroke of the piston in the measuring chamber, and the variation of different measuring specifications within a certain range can be quickly realized to adapt to the change of the drug density. The quantity is randomly adjusted or adjusted for the production of other specifications. The drug metering for each channel is designed as a separate unit, and the same metering system can accommodate metering of particles, powders or pills. Since the measures have been taken in the design, the gravity change of the material in the hopper and the influence of the air on the measurement accuracy are eliminated during the metering of the medicine, so that the measurement accuracy can be stably controlled at a high level without any effort, especially in the The effect is very significant when measuring micro-products or medium-medicine materials. In China, there has been a record of 1% stable loading accuracy for users at 1 gram.

In addition, Medicis has a strong ability to meet the special technical requirements of users. It has provided a special metering device for filling a two different medicines in the same pouch for a Chinese pharmaceutical company, so that users can solve the problem in the process. Ensure that the two drugs are evenly mixed.

The seal meets the four sides of the "airtight" and shaped bag design

The four sealing edges of the pouch are sealed in the process of forming the bottom edge and the two longitudinal sealing edges, and then the filling medicine is filled, and the lower end of the filling tube is below the upper sealing edge to avoid contamination of the upper sealing edge of the medicine material during filling. . In addition, the bag making, filling, and capping steps are completed in steps to ensure the reliability of the seal. The sealing mold of the pouch is in the form of flat plate flat pressure, the pressure is stable and the pressure value can be displayed and verified. The pressure supply system is an advanced hydraulic structure that provides flexible pressure with stable pressure. It is cushioned, vibration-damped and low-noise during operation, making the mold reliable and durable. The sealing temperature is steplessly adjustable and the temperature value can be displayed. The pressure and temperature parameters can be adjusted to match each other to achieve a combination of optimal sealing parameters for different sealing materials. Another benefit of the flat-form form of the bag is that it can produce shaped pouch packaging to meet the design of the pouch that highlights the corporate and product image.

When the machine is shut down, the heating parts of the small bag packaging machine will be completely opened to both sides and completely separated from the medicine and packaging materials, so as to prevent the medicine and packaging materials from being overheated and damaged. After restarting, it automatically returns to the position and automatically detects that the sealed working pressure is at the set value before continuing to run.

Change the size of the pouch and the splicing of the packaging material.

If you need to change the pull length of the pouch, you can set it through the operation screen, servo motor drive, steplessly adjustable in the working range to meet the length variation of different product packaging specifications.

When the packaging film material is used up, the machine will automatically stop. At the same time, the packaging film can be automatically fixed on the splicing table by vacuum adsorption on the splicing table, which is convenient for the operator to replace the new film roll and splicing. At the same time, the machine will detect the splicing part of the packaging film. When the splicing part reaches the filling station, the machine will automatically close the feeding system, and the medicine will not be filled in the spliced ​​pouch, and the empty bag will be automatically rejected online.

Palletizing plays an important "hub" role

The pouch palletizing device is an important hub for connecting the front section pouch packaging machine and the rear section cartoning machine. The small bag that is slit on the pouch packaging machine is placed on the inclined conveyor system by a vacuum nozzle and enters the pouch palletizing device. Here, the sampling of the product, the counting and stacking of the pouches, the finishing of the pouches, and the input of the pouches into the cartoning machine are completed. The important thing here is the finishing of the small bag. Generally, the finishing of the small bag is divided into two steps: firstly, each small bag is leveled, and the material is evenly distributed in the small bag by gentle horizontal shaking, thereby maintaining the overall stability of the small bag after stacking. Sex. The second step is to carry out the finishing of the small bag after the palletizing, so as to ensure that the small bag is sent into the cartoning machine and the subsequent order into the carton is always in a stable state.

Rear intermittent cartoning machine is especially important

The cartoning machine is a key position in the entire production line. Its reliability, stability, and linkage characteristics will directly affect the efficiency of continuous and finished products. Since the operation mode of the front-end equipment is intermittent, the post-intermittent operation of the cartoning machine is particularly important, so that the individual machines can be integrated. Germany Medici Co., Ltd. can provide automatic batch cartoning machines of different specifications and models according to the user's production requirements. In the production, the folding of the manual, the insertion of the small bag, and the printing of the batch number are automatically completed. Since the four-side sealed pouch is packaged in a flexible package, it is necessary to avoid the top pressure in the process of entering the carton. Therefore, the company has adopted the pre-boxing device in the design of the device, so that the manual and the pouch are separately entered. Tray. When the carton and manual are less than the minimum stock, the machine will automatically alarm, prompting the operator to add it in time.

In this era of continuous expansion of the industry and the emergence of new technologies, Medicis has always been recognized as the authoritative representative of small bag packaging technology. Regardless of the technology of a major breakthrough or the details of the company, Medicis hopes to serve the present and future of this field with diamond-like quality and perfect posture.