Product Name: Tacrolimus
Synonyms: (2-propenyl)-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*,8s*,9e,12r*,14r*,15s*,16r*,18s*;,19s*,26ar*))-;16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1;19-epoxy-3h-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4h,23h)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dim;6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-5;fr900506;prograf;tsukubaenolide
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Tacrolimus Usage And Synthesis
Chemical Properties White Crystalline Solid
Usage An immunosuppressant that blocks TÂ cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.
Usage FK-506 (Tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system
Usage Tacrolimus (fujimycin) was discovered as a potent inhibitor of IL2 production in a targeted search for novel immunosuppressants. Tacrolimus acts by blocking T cell proliferation in vitro by inhibiting the generation of several lymphokines, notably the original target IL-2. Tacrolimus inhibits the activity of FK-506 binding protein, Ca2+-dependent phosphatase and calcineurin, and activates NF-κB through phosphorylation and degradation of IκBα.
Usage treatment of Cushing's syndrome
Usage For use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver transplantation, this has been extended to include kidney, heart,
Wuhan dongkangyuan technology co., LTD. Is a high-tech industrial company specializing in
the r&d and sales of chemical raw materials in central China.Telephone 027-81302558,
15377521700 QÂ Q: 2851686514
Products are as follows:
isoniazid   CAS  54-85-3
chloramphenicol CASÂ Â 56-75-7
clotrimazole  CAS 23593-75-1
11-alpha-Hydroxycarvenone CASÂ Â 192569-17-8
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CAS 104987-11-3 drugs API Tacrolimus Chemical Now The Price IÂ Know
Product Name: Tacrolimus
Synonyms: (2-propenyl)-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*,8s*,9e,12r*,14r*,15s*,16r*,18s*;,19s*,26ar*))-;16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1;19-epoxy-3h-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4h,23h)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dim;6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-5;fr900506;prograf;tsukubaenolide
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Tacrolimus Usage And Synthesis
Chemical Properties White Crystalline Solid
Usage An immunosuppressant that blocks TÂ cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.
Usage FK-506 (Tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system
Usage Tacrolimus (fujimycin) was discovered as a potent inhibitor of IL2 production in a targeted search for novel immunosuppressants. Tacrolimus acts by blocking T cell proliferation in vitro by inhibiting the generation of several lymphokines, notably the original target IL-2. Tacrolimus inhibits the activity of FK-506 binding protein, Ca2+-dependent phosphatase and calcineurin, and activates NF-κB through phosphorylation and degradation of IκBα.
Usage treatment of Cushing's syndrome
Usage For use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver transplantation, this has been extended to include kidney, heart,
Wuhan dongkangyuan technology co., LTD. Is a high-tech industrial company specializing in
the r&d and sales of chemical raw materials in central China.Telephone 027-81302558,
15377521700 QÂ Q: 2851686514
Products are as follows:
isoniazid   CAS  54-85-3
chloramphenicol CASÂ Â 56-75-7
clotrimazole  CAS 23593-75-1
11-alpha-Hydroxycarvenone CASÂ Â 192569-17-8
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Â
durabolinÂ
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CAS 104987-11-3 Drugs API Tacrolimus Chemical Now The Price I Know
Model NO.: 104987-11-3
Trademark: dky
Transport Package: Aluminum Foil or Cardboard Barrels
Specification: Pharmaceutical grade
Origin: Dky
Model NO.: 104987-11-3
Trademark: dky
Transport Package: Aluminum Foil or Cardboard Barrels
Specification: Pharmaceutical grade
Origin: Dky
CAS 104987-11-3 drugs API Tacrolimus Chemical Now The Price IÂ Know