Quick detail:
Full Name: (17-alpha,20E) 17,20-[(1-methoxyethylidene)bis(oxy)] 3-oxo-19-norpregna-4,20-diene 21-carboxylic acid methyl ester
Product Name: sarm yk11 1370003-76-1Â
Specification: ≥99% Â
Appearance: White fine Powder
Product Description
(17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11), which the myogenic differentiation of C2C12 myoblast cells is induced by the novel partial agonist. as well as by .
Â
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells. The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Â
Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products. YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic  properties of YK11
Â
Fuction:
It induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as  differentiation  8, is a myokine (protein) produced by muscle cells that acts on muscle cells to inhibit myogenesis. Myogenesis is muscle cell growth and differentiation. Research through the years show that when you block myostatin, it allows for significantly more muscle mass. So in research myostatin  are researched to find cures for muscle diseases.
Â
We expect YK11 to be more potent than SARM LGD in terms of overall growth and feel. At this time, we expect this to be the strongest SARM on the market at a regular dosing. While suppression can occur, we expect this product to have low androgenic properties and can be used by both men and women. From our experience with SARMs, we find there are less losses of on-cycle results than pro-, although typically not as potent. We do expect this product to have similar results as a moderately dosed Halodrol, without the alpha-male/androgenic feelings while on it.
Other SARMs
Name
CAS NO.
Usage
AICAR
2627-69-2
acts by entering nucleoside pools, significantly increasing levels of adenosineÂ
during periods of ATP breakdown
MK2866
841205-47-8
medical prescription for prevention of cachexia, atrophy, and sarcopenia andÂ
for Hormone or Testoserone Replacement Therapy.
MK-677
15972-10-0
Â
for the treatment of frailty in the elderly
LGD-4033
1165910-22-4
pharmacological profile similar to that of enobosarm, Ostarine,MK-2866
GW1516
317318-70-0
For obesity, diabetes, dyslipidemia and cardiovascular disease
Andarine(S4)
401900-40-0
partial agonist, intended mainly for treatment of benign prostatic hypertrophy
SR9009
1379686-30-2
under development at The Scripps Research Institute (TSRI),Â
increases the level of metabolic activity in skeletal muscles of mice
RAD140
1182367-47-0
New generation for gaining mass and cutting edges
YK11
431579-34-9
YK11: a SARM and myostatin inhibitor in one
Â
AC262356
870888-46-3
New SARMS
SR9011
1379686-29-9
New SARMS
S23
1010396-29-8
New SARMS
GW0724
317318-84-6
New SARMS
Hubei Zhaoke Bio-Chemical Co., Ltd.is a leading Chinese Pharmaceutical Ingredient supplier special in Steroi hormon powder,Male sex enhancement powder and Anti-breast cancer powder.Such as Test enanthat,Test cypionat,Sus250, Anav,Nandr decanoat/phenypropionat,Methen acetat/enanthat,Trenb acetat/enanthat,Drost enanthat/Propionat,Bold undecylenat/acetat,Sarms powder...Our company supply preferential price and high quality products.We invest large fund and brains into R&D, developing new products and pioneering new technics, to meet the demand of the market. All the products from our plants are the fruit of out R&D department, reaching the advanced standard of domestic market, many of which reach the international standard.
NO.
Product Name:
Label:
1
Testoste base
TB
2
Testoste EnanthatÂ
TE
3
Testoste Cypionat
TC
4
Testoste Acetat
TA
5
Testoste Propionat
TP
6
Testoste Decanoat
TD
7
Testoste Phenylpropionat
TPP
8
Testoste Blend / Sustan250
S250
9
Testoste Undecanoat / Andri
TU
10
Testoste Isocaproat
TI
Â
11
Mestero / Provir
Prov
12
17a-Methyl-1-testoste
17MT
13
4-chlorinedehydro-methyl testoste/Turinab
CH
14
Methyl drostanol / Superdl /Methaste
Sup
15
Fluoxymestero / Halotest
Flou
16
Methyltestoste
MT
17
4-Chlorotestoste Acetate/Closteb acetat
4CA
18
Mestanolo
Mest
19
Dehydroepiandrostero
Dhe
20
7-Keto-dehydroepiandrostero
7Dhe
Â
21
Oxandro / Anav
OA
22
Metandien / Diana
DB
23
Oxymetho / Anadr
Oxy
24
Stanoz / winstr
ST
25
Bolde undecanoat / Equipo
EQ
26
Bolde Acetat
BA
27
Bolde base
BB
28
Bolde Cypionat
BC
29
Bolde Propionat
BP
30
Nandr Decanoat
ND
Â
31
Nandr Phenylpropiona
NP
32
Nandr base
NB
33
Nandr Cypionat
NC
34
Nandr Undecylat
NU
35
Trenbo Acetat
TBA
36
Trenbo Enanthat
TBE
37
Trenbo Hexahydrobenzyl carbonate / Parabol
TBH
38
Trenbo Base
TBB
39
Drostanol Propionat / Â Master Propionat
DP
40
Drostanol Enanthat / Master Enanthat
DE
Â
41
Methenolo Acetat / Primobo Acetat
MA
42
Methenolo Enanthat / Primobol Enanthat
ME
43
Tamoxif Citrate / Nolvad
Nol
44
Clomiph Citrate / Clom
Clo
45
Letr / Letraz / Fema
Let
46
Anastro / Arimi
Ari
47
Exemest /Aromas
Exe
48
Formest / Lentar
Form
49
Cytomel T3 / Liothyronine sodium
T3
50
L-Thyroxine/ T4 /Â tetraiodothyronine
T4
Â
51
Sildena / Viag
Sil
52
Tadalaf Citrate / Ciali
Cia
53
Vardena / Fardena / Levit
Var
54
Dapoxeti / Prili
Dap
55
Yohimbine Hydrochloride / Corynine / Aphrodine
Yoh
56
Dutasteri / Avoda
Dut
57
Finasteri / Prosc
Fin
58
GW 0742
G07
59
SR9011
S11
60
AC262356
AC2
Â
61
MK-677 (Nutrobal / Ibutamore)
M6
62
MK-2866 (ostarine)
M2
63
LGD-4033 (Anabolicum)
LGD
64
SR9009
S09
65
GW 501516 (Cardarine)
G50
66
S-4 (Andarine)
S4
67
S-23
S23
68
RAD-140
RAD
69
YK-11
YK
70
AICAR
AIC
Â
71
GH 10IU/vial
GH
72
CG 5000IU/vial
CG
73
GH raw poder
GHP
74
Melanotan 2 / MT2
MT2
75
Ghrp 2
G2
76
Ghrp 6
G6
77
Cjc 1295
Cjc
78
L-carnitine
Carn
79
Benzocain Hydrochloride
Benz
80
Lidocain Hydrochloride
Lido
Q1:Can I get some samples?
A:Sure,we can supply the free sample,but the shipping cost be paid buy our customers.
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Q2:How to make orders?
A:Please send inquiry to us,after we come to an agreement,send payment via Western Union,Moneygram or Bank account,then we ship products out and give tracking number to you.
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Q3:How to delivery?
A:Pack shipped in 3 days(Chinese holiday not included) after payment,usually ship via EMS,HKEMS,DHL,TNT,FedEx,UPS...
If there any troubles with shipping address,we will ship with specail safe and hidden packages,to guarantee you get packs without problems.
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Q4:Is there any discount?
A:Yes.The price is negotiable,If you order large quantity or some products together,you will get discount.
Â
Q5:What is the Minimum order quantity?
A:The Min. order quantity according to your request,10g,50g all is OK.
But the price according to the order quantity,the larger the order is,the better the price is.
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Q6:How to handle quality complaints?
A:Our quality control will reduce the quality to near zero,but if there is a quality problem caused by us,we will ship free products for replacement or refund your loss.
1. Top quality and factory price,a discount would be given when you make a large order.
2. Rich experienced in delivering,package will be reshipped if sent failed.
3. Enough stock ensure the prompt delivery time.
4. Good after-sales service,any of your question would be solved for the first as soon as possible.
5. Adhering to the principle of customer first conviction,we will provide the best and the most sincere services as possible as we can.
Â
Quick detail:
Full Name: (17-alpha,20E) 17,20-[(1-methoxyethylidene)bis(oxy)] 3-oxo-19-norpregna-4,20-diene 21-carboxylic acid methyl ester
Product Name: sarm yk11 1370003-76-1Â
Specification: ≥99% Â
Appearance: White fine Powder
Product Description
(17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11), which the myogenic differentiation of C2C12 myoblast cells is induced by the novel partial agonist. as well as by .
Â
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells. The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Â
Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products. YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic  properties of YK11
Â
Fuction:
It induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as  differentiation  8, is a myokine (protein) produced by muscle cells that acts on muscle cells to inhibit myogenesis. Myogenesis is muscle cell growth and differentiation. Research through the years show that when you block myostatin, it allows for significantly more muscle mass. So in research myostatin  are researched to find cures for muscle diseases.
Â
We expect YK11 to be more potent than SARM LGD in terms of overall growth and feel. At this time, we expect this to be the strongest SARM on the market at a regular dosing. While suppression can occur, we expect this product to have low androgenic properties and can be used by both men and women. From our experience with SARMs, we find there are less losses of on-cycle results than pro-, although typically not as potent. We do expect this product to have similar results as a moderately dosed Halodrol, without the alpha-male/androgenic feelings while on it.
Other SARMs
Name
CAS NO.
Usage
AICAR
2627-69-2
acts by entering nucleoside pools, significantly increasing levels of adenosineÂ
during periods of ATP breakdown
MK2866
841205-47-8
medical prescription for prevention of cachexia, atrophy, and sarcopenia andÂ
for Hormone or Testoserone Replacement Therapy.
MK-677
15972-10-0
Â
for the treatment of frailty in the elderly
LGD-4033
1165910-22-4
pharmacological profile similar to that of enobosarm, Ostarine,MK-2866
GW1516
317318-70-0
For obesity, diabetes, dyslipidemia and cardiovascular disease
Andarine(S4)
401900-40-0
partial agonist, intended mainly for treatment of benign prostatic hypertrophy
SR9009
1379686-30-2
under development at The Scripps Research Institute (TSRI),Â
increases the level of metabolic activity in skeletal muscles of mice
RAD140
1182367-47-0
New generation for gaining mass and cutting edges
Yk11 Weight Loss Powder Yk-11 Sarms Powder
Model NO.: CAS: 431579-34-9
Price: Factory Price and Negotiable
Shipping: Gurantee Success Delivery
Trademark: ZK
Transport Package: Different Kinds of Special Packing Methods
Specification: USP EP CP BP
Origin: China
Model NO.: CAS: 431579-34-9
Price: Factory Price and Negotiable
Shipping: Gurantee Success Delivery
Trademark: ZK
Transport Package: Different Kinds of Special Packing Methods
Specification: USP EP CP BP
Origin: China